BioMed Research International
BMRI
- URL: https://www.hindawi.com/journals/BMRI/si/438650/cfp/?utm_source=CFPsites&utm_medium=marketing%20referral&utm_campaign=HDW_MRKT_GBL_SUB_CFP_EAR_AUTH_SPEC_2738_10053
- Call For Paper Type: SI
- H2 Index: 0
- Submission Date: 2019-11-01
- Notification Date: 2019-12-01
- Final Version Date: 2020-02-28
Health & Medical Sciences (General) Orthopedic Medicine & Surgery Rheumatology
Osteoarthritis is the most common degenerative joint disease, causing pain and immobilization and creating a huge economic burden. Traditionally osteoarthritis has been thought to be a disease of articular cartilage, but it is currently accepted to be a disease of the whole joint. Various osteoarthritis-related modifications have been identified in both subchondral bone and calcified cartilage. Furthermore, the subchondral bone is an attractive target for pharmacological treatments due to its high metabolic activity and remodeling. However, the osteoarthritis-derived alterations in subchondral bone and calcified cartilage (especially those concomitant with articular cartilage) and specifically the role of these changes in initiation and progression of osteoarthritis remain elusive. Understanding the concomitant and independent alterations in articular cartilage, calcified cartilage, and subchondral bone, together with the crosstalk between these tissues in osteoarthritis, may be the key towards novel inhibitive or progress preventative treatments of osteoarthritis.
In this special issue, the fundamental modifications of subchondral bone in osteoarthritis will be discussed through original research articles and comprehensive review articles.
Submissions that further the understanding of changes that occur during osteoarthritis, such as morphological, compositional, vascular, and mechanical (micro- and nanoscale) changes, including computational modeling techniques, are welcomed. A demonstration of conceptual understanding of the crosstalk between subchondral bone and the articular cartilage, supported by a combination of analysis techniques, is especially welcomed. Furthermore, in vivo and in vitro studies on subchondral bone-targeted drug treatments as well as mechanisms and crosstalk between subchondral bone and articular cartilage are encouraged.
Potential topics include but are not limited to the following:
Osteoarthritis-related alterations in subchondral bone
Concomitant and independent modifications in subchondral bone, calcified cartilage, and articular cartilage during osteoarthritis
Crosstalk between tissues in osteochondral junction during osteoarthritis
Animal models of osteoarthritis and preclinical studies on osteoarthritis treatment
Development of tools for analysis of osteoarthritic alterations in subchondral bone, calcified cartilage, and articular cartilage
Lead Guest Editor:
Mikael J. Turunen, University of Eastern Finland, Kuopio, Finland
Guest Editors:
Petri Tanska, University of Eastern Finland, Kuopio, Finland
Mikko Finnilä, Oulu University, Oulu, Finland
Sander Botter, Swiss Center for Musculoskeletal Biobanking (SCMB), Zürich, Switzerland
Authors can submit their manuscripts through the Manuscript Tracking System at https://mts.hindawi.com/submit/journals/bmri/orthopedics/osbca/
Submission Deadline:
Friday, 1 November 2019
Publication Date:
March 2020
Papers are published upon acceptance, regardless of the Special Issue publication date
Journal Promotion
|
| Acta Koreana (Acta Koreana) |
|
| Acta Via Serica (AVS) |
|
| Computers and Concrete (CAC) |
|
| Journal of Information Processing Systems (JIPS) |
|
| Journal of Internet Computing and Services (KSII - JICS) |
|
| Journal of Smart Tourism (Smart Tourism) |
|
| Membrane and Water Treatment (MWT) |
|
| Wind and Structures, An International Journal (Wind and Structures) |
MANUSCRIPTLINK © 2015 -
