54th LISBON International Conference on Genetics, Cellular and Molecular Biology (LGCMB-26) Dec. 9-11, 2026 Lisbon (Portugal)

LGCMB-26


Bioinformatics & Computational Biology Genetics & Genomics Molecular Biology Cell Biology Evolutionary Biology Microbiology Molecular Biology Biodiversity & Conservation Biology



Topics



All Abstracts, Reviews, short articles, Full articles, Posters are welcomed related with any of the following research fields:



1. Molecular Biology 



Molecular biology focuses on the chemical substances and processes involved in biological activity at the molecular level.



The Central Dogma





  • DNA Structure & Topology: Double helix, supercoiling, and chromatin packaging.




  • DNA Replication: Semiconservative models, replication forks, and telomere maintenance.




  • Transcription: RNA polymerase, promoters, enhancers, and the formation of pre-mRNA.




  • RNA Processing: Splicing (introns/exons), 5' capping, and polyadenylation.




  • Translation: Ribosome structure, tRNA charging, and polypeptide synthesis.





Gene Regulation & Epigenetics





  • Prokaryotic Regulation: Operons (e.g., lac and trp operons).




  • Eukaryotic Regulation: Transcription factors and distal regulatory elements.




  • Epigenetics: DNA methylation, histone acetylation, and chromatin remodeling.




  • Non-coding RNA: miRNA, siRNA, and lncRNA in gene silencing.





Molecular Techniques





  • Recombinant DNA: Cloning, restriction enzymes, and plasmids.




  • Amplification & Sequencing: PCR (Polymerase Chain Reaction), Sanger sequencing, and Next-Generation Sequencing (NGS).




  • Genome Editing: CRISPR-Cas9, ZFNs, and TALENs.





2. Genetics 



Genetics is the study of genes, genetic variation, and heredity in organisms.



Classical (Mendelian) Genetics





  • Laws of Inheritance: Segregation, Independent Assortment, and Dominance.




  • Non-Mendelian Inheritance: Incomplete dominance, codominance, and polygenic traits.




  • Sex-linked Inheritance: X-linked and Y-linked traits.





Cytogenetics & Chromosomal Theory





  • Karyotyping: Chromosome mapping and identification.




  • Chromosomal Aberrations: Aneuploidy (e.g., Trisomy 21), deletions, duplications, and translocations.




  • Linkage and Mapping: Genetic recombination and crossover frequencies.





Population & Evolutionary Genetics





  • Hardy-Weinberg Equilibrium: Calculating allele frequencies in stable populations.




  • Forces of Evolution: Mutation, gene flow, genetic drift, and natural selection.




  • Quantitative Genetics: Heritability and continuous variation.





Human & Medical Genetics





  • Pedigree Analysis: Tracking traits through generations.




  • Genetic Disorders: Inborn errors of metabolism, monogenic vs. multifactorial diseases.




  • Pharmacogenomics: How genes affect an individual’s response to drugs.





3. Cellular Biology



Cell biology deals with the physical structure, physiological properties, and life cycle of the cell.



Cell Structure & Function





  • Organelles: Nucleus, Mitochondria (bioenergetics), Ribosomes, Endoplasmic Reticulum, and Golgi apparatus.




  • Membrane Dynamics: Fluid mosaic model, active/passive transport, and endocytosis/exocytosis.




  • The Cytoskeleton: Microtubules, microfilaments, and intermediate filaments.





The Cell Cycle & Division





  • Mitosis: Stages of somatic cell division ($G_1, S, G_2, M$).




  • Meiosis: Gamete formation and genetic shuffling.




  • Cell Cycle Control: Checkpoints, cyclins, and CDKs (Cyclin-Dependent Kinases).





Cell Signaling & Communication





  • Signal Transduction: Receptors (GPCRs, RTKs), second messengers (cAMP, $Ca^{2+}$), and phosphorylation cascades.




  • Apoptosis: Programmed cell death pathways (intrinsic vs. extrinsic).





Metabolic Pathways





  • Glycolysis & Respiration: Energy extraction from glucose.




  • Photosynthesis: Light-dependent and light-independent reactions (in plant cells).




  • Protein Sorting: The secretory pathway and protein targeting (signal peptides).





Interrelated "Bridge" Topics



These fields exist specifically at the intersection of the three main categories:





  • Cancer Biology: Genetics (mutations), Molecular Biology (oncogenes), and Cell Biology (uncontrolled division).




  • Developmental Biology: How gene expression (Molecular) drives cell differentiation (Cellular) to form an organism.




  • Genomics & Proteomics: Large-scale study of the entire genome and the resulting protein set.




  • Synthetic Biology: Re-engineering biological systems using molecular tools.