WGCMB-26
Molecular Modeling Genetics & Genomics Molecular Biology Nuclear Medicine, Radiotherapy & Molecular Imaging
Topics of Interest for Submission include, but are Not Limited to:
The study of the molecular basis of biological activity, focusing on the interactions between DNA, RNA, and protein biosynthesis.
The Central Dogma
DNA Structure and Topology (B-DNA, A-DNA, Z-DNA)
DNA Replication (Prokaryotic vs. Eukaryotic)
DNA Repair Mechanisms (Mismatch, Excision, and Double-strand break repair)
Transcription (Initiation, Elongation, Termination)
RNA Processing (Splicing, 5' Capping, Polyadenylation)
Translation (Ribosome structure, Genetic code, tRNA charging)
Gene Regulation
Operon Models (lac, trp)
Transcriptional Control (Enhancers, Silencers, Transcription Factors)
Post-transcriptional Control (RNA interference, miRNA, siRNA)
Translational and Post-translational Modifications
Techniques & Tools
Polymerase Chain Reaction (PCR) and its variants (qPCR, RT-PCR)
Gel Electrophoresis (DNA, RNA, and Proteins)
Molecular Cloning and Restriction Digestion
Blotting Techniques (Southern, Northern, Western)
Next-Generation Sequencing (NGS)
The study of cell structure and function, including the physiological properties and life cycle of the cell.
Cell Structure and Organelles
Cell Membrane Dynamics (Fluid Mosaic Model, Lipid Rafts)
The Nucleus (Chromatin organization, Nuclear pore complex)
The Endomembrane System (ER, Golgi Apparatus, Lysosomes)
Energy Converters (Mitochondria and Chloroplasts)
The Cytoskeleton (Microtubules, Microfilaments, Intermediate Filaments)
Cellular Metabolism and Transport
Passive and Active Transport (Channels, Pumps, Vesicular Transport)
Bioenergetics (Glycolysis, Krebs Cycle, Oxidative Phosphorylation)
Signal Transduction (G-protein coupled receptors, Tyrosine Kinases)
Cell Cycle and Development
Mitosis and Meiosis (Stages and Regulation)
Cell Cycle Checkpoints and Cyclin-CDK Complexes
Apoptosis (Programmed Cell Death) vs. Necrosis
Stem Cell Biology and Differentiation
The study of heredity and the variation of inherited characteristics.
Classical (Mendelian) Genetics
Mendel’s Laws (Segregation and Independent Assortment)
Monohybrid and Dihybrid Crosses
Non-Mendelian Inheritance (Incomplete Dominance, Codominance, Epistasis)
Sex-linked Inheritance and Pedigree Analysis
Molecular Genetics & Cytogenetics
Chromosome Structure and Karyotyping
Genetic Linkage and Mapping
Mutations (Point mutations, Frameshifts, Chromosomal Aberrations)
Transposable Elements (Transposons)
Population and Evolutionary Genetics
Hardy-Weinberg Equilibrium
Genetic Drift, Gene Flow, and Natural Selection
Quantitative Trait Loci (QTL)
Epigenetics
DNA Methylation
Histone Acetylation and Modification
Genomic Imprinting
Advanced areas where these three disciplines converge with other sciences.
Genomics and Proteomics
Structural, Functional, and Comparative Genomics
Protein Profiling and Mass Spectrometry
Bioinformatics
Sequence Alignment (BLAST)
Phylogenetic Tree Construction
Computational Modeling of Biological Systems
Biotechnology & Medical Applications
CRISPR-Cas9 and Genome Editing
Gene Therapy and Personalized Medicine
Cancer Biology (Oncogenes and Tumor Suppressors)